Response to Aortic Pulse Wave Velocity, Reflection Site Distance, and Augmentation Index

Aortic pulse wave velocity, reflection site distance, and augmentation index.

Augmentation index and aortic pulse wave velocity in patients with abdominal aortic aneurysms.

BACKGROUND Abdominal aortic aneurysm (AAA) is a severe disease that can prove fatal. Factors such as advanced age, male gender, family history and cigarette use increase the risk of AAA. These factors associated with AAA development also increase arterial stiffness. Aortic pulse-wave velocity (PWV) was measured as an index of aortic stiffness. The heart rate-corrected augmentation index (AIx@75...

The 24-hour pulse wave velocity, aortic augmentation index, and central blood pressure in normotensive volunteers

The purpose of this study was to examine the pulse wave velocity, aortic augmentation index corrected for heart rate 75 (AIx@75), and central systolic and diastolic blood pressure during 24-hour monitoring in normotensive volunteers. Overall, 467 subjects (206 men and 261 women) were recruited in this study. Participants were excluded from the study if they were less than 19 years of age, had b...

Vasoactive drugs influence aortic augmentation index independently of pulse-wave velocity in healthy men.

Aortic augmentation index, a measure of central systolic blood pressure augmentation arising mainly from pressure-wave reflection, increases with vascular aging. The augmentation index is influenced by aortic pulse-wave velocity (related to aortic stiffness) and by the site and extent of wave reflection. To clarify the relative influence of pulse-wave velocity and wave reflection on the augment...

Location of a reflection site is elusive: consequences for the calculation of aortic pulse wave velocity.

Aortic pulse wave velocity (PWV), a measure of aortic stiffness, is an important indicator of cardiovascular risk. Derivation of PWV from uncalibrated proximal aortic or carotid pressure alone has practical advantages. However, when the time of return of the reflected wave, (Delta)t, is used to calculate PWV, inaccurate data are obtained. With aging PWV increases but (Delta)t hardly decreases, ...